Table 1.

UCLA Scoring System for Assigning Level of Suspicion to Regions of Interest (ROI) Found in the Prostate on Multi-Parametric MRI (mpMRI)^*

Image grade	T2-weighted imaging (T2WI)	Apparent diffusion coefficient (ADC)	Dynamic contrast enhancement (DCE)
1	Normal	>1.2 × 10−3 mm2/s	Normal
2	Faint decreased signal	1.0-1.2 × 10−3 mm2/s	Mildly abnormal enhancement
3	Moderately dark nodule	0.8-1.0 × 10−3 mm2/s	Moderately abnormal enhancement
4	Intensely dark nodule	0.6-0.8 × 10−3 mm2/s	Highly abnormal enhancement
5	Dark nodule with mass effect	<0.6 × 10−3 mm2/s	Profoundly abnormal enhancement

^*The higher the score, the greater the level of suspicion. Regions of interest with scores of 1 and 2 are no more likely to contain cancer than normal tissue and are not usually targeted. A score of 5 indicates cancer in most cases. From Sonn GA, Natarajan S, Margolis DJ, et al. Targeted biopsy in the detection of prostate cancer using an office based magnetic resonance ultrasound fusion device. The Journal of urology. Jan 2013;189(1):86-91; with permission.