Table 3.

Change in blood parameters

			Intervention group
Characteristics		Control group ( n  = 7)	p value	Intake frequency of <50% ile ( n  = 12)	p value	Intake frequency of ≥50% ile ( n  = 16)	p value
	Baseline	185 ± 32		222 ± 26		211 ± 27
T-Chol (mg/dL)			0.191*		0.229*		0.006*
	After 3 months	199 ± 40		215 ± 28		199 ± 22
	Baseline	105 ± 44		136 ± 30		127 ± 31
LDL-Chol (mg/dL)			0.292*		0.437*		0.010*
	After 3 months	109 ± 45		132 ± 26		116 ± 25
	Baseline	49 ± 17		53 ± 7		59 ± 11
HDL-Chol (mg/dL)			0.522*		0.287*		0.073*
	After 3 months	49 ± 16		51 ± 8		56 ± 15
	Baseline	240 ± 374		208 ± 116		121 ± 55
Triacylglycerol (mg/dL)			0.173†		0.136†		0.408†
	After 3 months	289 ± 436		181 ± 67		115 ± 51
	Baseline	113 ± 18		108 ± 19		118 ± 28
Glucose (mg/dL)			0.735†		0.583†		0.255†
	After 3 months	112 ± 21		107 ± 16		111 ± 18
	Baseline	5.0 ± 0.3		5.3 ± 0.5		5.5 ± 0.8
Hemoglobin A1C (%)			0.041†		0.033†		0.529†
	After 3 months	5.1 ± 0.2		5.4 ± 0.5		5.5 ± 0.7
	Baseline	3.5 ± 5.7		1.4 ± 2.0		1.9 ± 5.9
Active ghrelin (fmol/mL)			0.128†		0.008†		.001†
	After 3 months	6.4 ± 7.4		3.8 ± 3.9		5.3 ± 8.4
	Baseline	133.2 ± 161.2		41.6 ± 49.0		77.4 ± 135.4
Desacyl ghrelin (fmol/mL)			1.000†		0.002†		0.001†
	After 3 months	108.0 ± 67.7		101.4 ± 89.3		115.7 ± 180.7
	Baseline	1692 ± 1903		3611 ± 2786		1797 ± 999
Leptin (pg/mL)			0.074*		0.001*		0.000†
	After 3 months	308 ± 219		610 ± 391		313 ± 158

Data shows mean ± S.D. Abbreviations: T-Chol Total cholesterol, LDL-Chol Low-density lipoprotein cholesterol, HDL-Chol high-density lipoprotein cholesterol. *p stands for the difference between the baseline parameters and the parameters after 3 months analyzed by the paired t-test. †p stands for the difference between the baseline parameters and the parameters after 3 months analyzed by Wilcoxon’s signed rank test. Difference was considered significant at p < 0.05.