Table 3.
Subject self-assessment of efficacy (last observation carried forward)
| Trial #1. Female 9-beam | Trial #2. Female 12-beam | Trials #3 and #4. Male 7-, 9- and 12-beam (pooled) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Overall improvement of hair loss condition | Thickness and fullness of hair | Overall improvement of hair loss condition | Thickness and fullness of hair | Overall improvement of hair loss condition | Thickness and fullness of hair | |||||||
| Lasercomb (n = 43) | Sham (n = 22) | Lasercomb (n = 43) | Sham (n = 22) | Lasercomb (n = 39) | Sham (n = 18) | Lasercomb (n = 39) | Sham (n = 18) | Lasercomb (n = 67) | Sham (n = 36) | Lasercomb (n = 67) | Sham (n = 36) | |
| Week 16 (LOCF), n (%) | ||||||||||||
| Improved/ minimally improved | 36 (83.7) | 12 (54.5) | 28 (65.1) | 8 (36.4) | 25 (64.1) | 7 (38.9) | 23 (59.0) | 8 (44.4) | 39 (58.2) | 12 (33.3) | 37 (55.2) | 15 (41.7) |
| No change | 7 (16.3) | 9 (40.9) | 15 (34.9) | 14 (63.6) | 11 (28.2) | 9 (50.0) | 15 (38.5) | 10 (55.6) | 27 (40.3) | 23 (63.9) | 28 (41.8) | 19 (52.8) |
| Worse/ minimally worse | 0 (0) | 1 (4.5) | 0 (0) | 0 (0) | 3 (7.7) | 2 (11.1) | 1 (2.6) | 0 (0) | 1 (1.5) | 1 (2.8) | 2 (3.0) | 2 (5.6) |
| p = 0.0149* | p = 0.0982 | p = 0.0546 | p = 0.2667 | p = 0.0706 | p = 0.2484 | |||||||
| Week 26 (LOCF), n (%) | ||||||||||||
| Improved/ minimally improved | 36 (83.7) | 11 (50.0) | 31 (72.1) | 10 (45.5) | 26 (66.7) | 11 (61.1) | 24 (61.5) | 9 (50.0) | 40 (59.7) | 17 (47.2) | 38 (56.7) | 13 (36.1) |
| No change | 6 (14.0) | 11 (50.0) | 12 (27.9) | 12 (54.5) | 11 (28.2) | 6 (33.3) | 14 (35.9) | 7 (38.9) | 25 (37.3) | 16 (44.4) | 28 (41.8) | 21 (58.3) |
| Worse/ minimally worse | 1 (2.3) | 0 (0) | 0 (0) | 0 (0) | 2 (5.1) | 1 (5.6) | 1 (2.6) | 2 (11.1) | 2 (3.0) | 3 (8.3) | 1 (1.5) | 2 (5.6) |
| p = 0.0321* | p = 0.0345* | p = 0.1713 | p = 0.1000 | p = 0.0717 | p = 0.0114* | |||||||
* Statistically significant
LOCF last observation carried forward