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. 2014 Mar 26;15:120. doi: 10.1186/1471-2164-15-120

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Copyright © 2014 Rye et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited.

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Nucleosome data at bp resolution reveal different nucleosome positioning. Nucleosome data at bp resolution reveal different nucleosome positioning around expressed and repressed RTSSs enriched for H3K4me2 in K562. Expressed RTSS nucleosome profiles display highly ordered nucleosome positioning, while this is not evident around repressed RTSSs, except for a well-positioned nucleosome exactly at the RTSS center. In contrast, expressed RTSSs generally display nucleosome depletion at the TSS center.