Table 1.
HIF1α inhibitors | No HIF1α inhibitors | P-value | |
---|---|---|---|
No of patients | 18 | 66 | |
Average age | 70 (54–84) | 63.9 (44–81) | 0.009 |
Median Gleason score | 7.5 (6–9) | 8 (6–10) | 0.747 |
Median PSA at start of androgen deprivation | 97 (0–5705) | 407 (0–4780) | 0.08 |
Percentage D'Amico high-risk disease (%) | 46 | 59 | 0.50 |
Median follow-up (years) | 3.2 (0.34–9.5) | 2.3 (1.0–8.5) | 0.099 |
HIF, hypoxia-inducible factor; PSA, prostate-specific antigen. The baseline characteristics of the patients with and without HIF1α inhibitor treatment are shown. Differences between the two groups were analyzed using Wilcoxon and Mann–Whitney U tests and P-values were calculated. The range is demonstrated within brackets.