Table 1.
Characteristics of the study population.
| Group | Patient | Number of biopsies | Age | Sex | Pky | Smoking status1 | COPD | Histology | Grade | Stage |
|---|---|---|---|---|---|---|---|---|---|---|
| Nonsmokers | NS-1 | 2 | 34 | M | 0 | No | ||||
| NS-2 | 5 | 48 | M | 0 | No | |||||
| NS-3 | 4 | 46 | M | 0 | No | |||||
| NS-4 | 3 | 53 | F | 0 | No | |||||
| Smokers without cancer | SNC-1 | 3 | 50 | M | 30 | Current | No | |||
| SNC-2 | 3 | 49 | M | 55 | Current | No | ||||
| SNC-3 | 3 | 46 | M | 50 | Current | No | ||||
| SNC-4 | 2 | 52 | M | 52 | Current | Yes | ||||
| SNC-5 | 3 | 61 | M | 60 | Current | No | ||||
| SNC-6 | 3 | 50 | M | 40 | Current | No | ||||
| SNC-7 | 3 | 68 | M | 48 | Current | Yes | ||||
| SNC-8 | 3 | 49 | M | 30 | Current | Yes | ||||
| SNC-9 | 3 | 36 | F | 32 | Current | No | ||||
| SNC-10 | 3 | 48 | F | 28 | Current | Yes | ||||
| SNC-11 | 3 | 61 | M | 50 | Current | No | ||||
| SNC-12 | 3 | 40 | M | 15 | Current | No | ||||
| SNC-13 | 3 | 65 | M | 45 | Current | Yes | ||||
| SNC-14 | 4 | 58 | M | 38 | Current | Yes | ||||
| SNC-15 | 3 | 59 | M | 39 | Current | No | ||||
| SNC-16 | 3 | 61 | M | 50 | Current | Yes | ||||
| Smokers with cancer | SC-1 | 3 | 63 | M | 80 | Former (12) | Yes | NSCLC—squamous cell carcinoma | T2 N2 M0 | IIIa |
| SC-2 | 2 | 45 | M | 50 | Current | Yes | HNC—squamous cell carcinoma | T2 N0 M0 | Ib | |
| SC-3 | 2 | 73 | M | 27 | Current | No | NSCLC—other type | T2 N0 M0 | Ib | |
| SC-4 | 3 | 68 | M | 60 | Current | Yes | NSCLC—adenosquamous carcinoma | T1 N0 M0 | Ia | |
| SC-5 | 1 | 60 | M | 60 | Current | Yes | NSCLC—squamous cell carcinoma | Tis N0 M0 | Ia | |
| SC-6 | 3 | 60 | M | 60 | Former (0.834) | No | NSCLC—squamous cell carcinoma | T4 N2 M0 | IIIb | |
| SC-7 | 2 | 44 | M | 36 | Current | No | NSCLC—adenocarcinoma | T1 N0 M0 | Ia | |
| SC-8 | 3 | 57 | M | 37 | Current | No | NSCLC—adenocarcinoma | T1 N0 M0 | Ia | |
| SC-9 | 2 | 52 | M | 28 | Current | No | NSCLC—other type | T2N0 M0 | Ib | |
| SC-10 | 3 | 48 | M | 52 | Current | No | HNC—squamous cell carcinoma | T4 N1 M0 | IIIa | |
| SC-11 | 3 | 58 | M | 38 | Current | Yes | HNC—squamous cell carcinoma | T2 N0 M0 | Ib | |
| SC-12 | 2 | 53 | M | 30 | Former (2) | Yes | HNC—squamous cell carcinoma | T4 N2 M0 | IIIb | |
| SC-13 | 3 | 52 | F | 32 | Current | Yes | NSCLC—squamous cell carcinoma | T3 N3 M1 | IV | |
| SC-14 | 3 | 53 | M | 20 | Current | Yes | NSCLC—adenocarcinoma | T1 N1 M1 | IV |
The percentage of males in the NS, SNC, and SC groups was 75%, 87.5%, and 92.9%, respectively, whereas the mean age for these groups was 45.25 (standard deviation (SD) 6.98), 53.31 (SD 8.67), and 56.14 (SD 8.00), respectively. The mean pack-years of smoking (pack-years; Pky) for the SNC and SC groups were 41.3 (SD 11.62) and 43.57 (SD 16.41), respectively, whereas the percentage of smokers with chronic obstructive pulmonary disease (COPD) in these groups was 43.75% and 51.14%, respectively. SNC, smokers without cancer; SC, single group; NSCLC, non-small cell lung cancer; HNC, head and neck cancer.
1
under (), years from smoking cessation to time of biopsy.