Table 2.
Adoptively transferred Vγ9Vδ2 T-cells
| Cell number (×108 cells) (purity of γδ T cells) |
Cumulative number of γδ T cell infusions (×108 cells) | Average number of γδ T cell infusions (×108 cells) | % cytotoxicity against z-Daudi* E/T ratio |
||||||
|---|---|---|---|---|---|---|---|---|---|
| Patient ID | First | Second | Third | Fourth | 1:1 | 5:1 | 25:1 | ||
| 2305 | 0.6 (27.6%) | 0.6 | 0.6 | 18.1 | 30.3 | 30.1 | |||
| 2307 | 58.8 (81.7%) | 58.8 | 58.8 | 31.4 | 40.9 | 53 | |||
| 2319 | 55.4 (77.0%) | 60.5 (84.0%) | 65.6 (85.2%) | 68.5 (85.6%) | 250 | 62.5 | 41.3 | 58 | 74.6 |
| 2325 | 49.7 (84.3%) | 60 (88.3%) | 69.8 (89.5%) | 40.1 (89.0%) | 219.6 | 54.9 | 14.2 | 39.3 | 60.2 |
| 2334 | 8.6 (71.5%) | 45.1 (77.8%) | 52.7 (82.3%) | 106.4 | 35.5 | 45.1 | 79.7 | 84.6 | |
| 2336 | 64.9 (94.0%) | 64.9 | 64.9 | 28.9 | 57 | 55.4 | |||
| 2328 | 62.4 (90.4%) | 59.2 (92.5%) | 65.7 (93.9%) | 51.7 (92.3%) | 239 | 59.8 | 38.3 | 64.5 | 72.2 |
*
% cytotoxicity against Daudi cells was provided in Table S2.