Table 2.
Patient characteristics according to HPV status and p53 expression.
| Characteristic | 0–60% p53-expression (n = 36) | 90–100% p53-expression (n = 14) | P |
|---|---|---|---|
| Gender, n (%) | |||
| Male | 28 (78) | 9 (64) | 0.329 |
| Female | 8 (22) | 5 (36) | |
| Mean age (years) | 65 | 65 | 0.994 |
| N stage, n (%) | |||
| 1 | 11 (31) | 3 (21) | 0.692 |
| 2 | 21 (58) | 10 (71) | |
| 3 | 4 (11) | 1 (7) | |
| Smoking history, n (%) | |||
| Yes | 24 (69) | 14 (100) | 0.021 |
| No | 11 (31) | 0 (0) | |
| HPV DNA | |||
| Positive | 17 (47) | 3 (21) | 0.118 |
| Negative | 19 (53) | 11 (79) | |
| p16 | |||
| Positive | 18 (50) | 3 (21) | 0.110 |
| Negative | 18 (50) | 11 (79) | |
| HPVDNA+/p16+ | |||
| Positive | 15 (42) | 3 (21) | 0.211 |
| Other | 21 (58) | 11 (79) | |
Comparison between patients with absent-intermediary/low (0–60%) and high (90–100%) p53 expression in their tumors (there were no patients with 61–89% p53 expression). Figures in parenthesis denotes %. HPV, human papillomavirus; N, nodal.