Table 2.
Pts | Year Dx | Baseline HBV DNA (copies/mL) | Anti-HBV therapy | HBV DNA (-) in months on anti-HBV therapy |
---|---|---|---|---|
1 | 2000 | 3.40 × 106 | LAM + TDF later | 3 |
2 | 2000 | 6.70 × 105 | LAM + TDF later | 8 |
3 | 2001 | 1.10 × 106 | LAM + TDF later | 5 |
4 | 2003 | 8.90 × 102 | LAM + ADV later | 10 |
5 | 2003 | 5.00 × 102 | LAM + TDF later | 6 |
6 | 2003 | 7.60 × 106 | LAM + TDF later | 9 |
7 | 2004 | 5.00 × 102 | LAM | 3 |
8 | 2004 | 3.30 × 105 | LAM + TDF | 3 |
9 | 2005 | 1.10 × 104 | LMM + ADV | 5 |
10 | 2006 | 1.00 × 107 | LAM + TDF | 8 |
11 | 2007 | 1.30 × 105 | TLV + TDF | 3 |
12 | 2008 | 4.40 × 102 | LAM + TDF | 1 |
131 | 2008 | 2.40 × 108 | LAM + ADV | 4 |
14 | 2009 | 1.40 × 107 | TLV + TDF | 7 |
15 | 2009 | 1.20 × 104 | TDF | 6 |
16 | 2010 | 1.40 × 105 | TDF | 5 |
LAM, lamivudine; TDF, tenofovir disoproxil fumarate; ADV, adefovir dipivoxil; TLV, telbivudine; HCC, hepatocellular carcinoma.
This patient discontinued antiviral drugs 1 year after HCC ablation. One year later (off medicine for a year), he returned with recurrent tumor and HBV DNA 2E + 09 (2 × 109 copies/mL). He died of HCC at 50 months after diagnosis.