Skip to main content
. 2014 Mar 25;11:13. doi: 10.1186/1743-8977-11-13

Table 1.

Physico-chemical characteristics of the TiO 2 -NP suspensions a

Dispersant Water Gastric Intestinal Ringer + FBS cDMEM
Z-average (nm)b
132.0 ± 0.8
218.4 ± 2.9
> 1000
352.0 ± 0.9
320.5 ± 1.8
PdIc
0.188
0.330
> 0.5
0.298
0.290
ζ (mV)d 20.0 ± 0.6 30.6 ± 2.7 -21.3 ± 0.7 -13.2 ± 1.2 -10.8 ± 0.6

aDLS measurements of a 50 μg/mL TiO2-NP suspension prepared either in water (“Water”), in the gastric phase (“Gastric” i.e. pepsin/HCl, pH2), in the intestinal phase (“Intestinal”, i.e. pepsin/HCl, pancreatin and bile extracts, pH7), in ex vivo exposure medium (“Ringer + FBS” i.e. Ringer solution, 10% (v/v) fetal bovine serum (FBS), pH7.4) or in in vitro exposure medium (cDMEM, i.e. Dulbecco Modified Medium (DMEM), 10% (v/v) FBS, pH7.4). bZ-average hydrodynamic diameter extracted by cumulant analysis of the data. cPolydispersity index (PdI) from cumulant fitting. dζ: zeta potential.

HHS Vulnerability Disclosure