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Analysis of type 1 diabetes–free survival in BBDP and congenic strains. The number of days to onset of diabetes is labeled on the horizontal axis. Data from the parental BBDP strain are compared with both the original double-congenic line and F1 offspring of the two. Both the congenic line and heterozygous animals have significantly decreased disease incidence compared with BBDP (P < 0.0001 and <0.0006 respectively, by Kaplan-Meier analysis log-rank statistic).
