Table 2.
Associations $ between different rapid progression of renal function definitions and traditional renal disease risk factors
| |
|
With at least three eGFR measurements |
With at least two eGFR measurements |
||||||
|---|---|---|---|---|---|---|---|---|---|
| Years of follow-up | Baseline variables |
RP definition A |
RP definition B |
RP definition A |
RP definition B |
||||
| OR (95% CI) | P | OR (95% CI) | P | OR (95% CI) | P | OR (95% CI) | P | ||
| Four |
Age >50 years |
1.90 (1.15-3.14) |
0.01 |
* |
2.33 (1.69-3.20) |
<0.001 |
2.65 (1.27-5.53) |
0.01 |
|
| Hypertension |
1.42 (0.85-2.37) |
0.19 |
1.41 (1.00-1.97) |
0.05 |
1.31 (0.55-3.10) |
0.54 |
|||
| Diabetes |
1.06 (0.44-2.54) |
0.90 |
0.88 (0.47-1.60) |
0.68 |
0.48 (0.06-3.62) |
0.48 |
|||
| Three |
Age >50 years |
1.91 (1.31-2.77) |
<0.001 |
2.75 (1.64-4.59) <0.001 |
2.07 (1.58-2.71) |
<0.001 |
2.80 (1.95-4.04) |
<0.001 |
|
| Hypertension |
1.58 (1.08-2.33) |
0.02 |
1.31 (0.71-2.40) 0.39 |
1.39 (1.04-1.85) |
0.03 |
0.79 (0.49-1.28) |
0.34 |
||
| Diabetes |
0.91 (0.45-1.83) |
0.64 |
1.16 (0.45-3.00) 0.76 |
0.94 (0.56-1.59) |
0.82 |
1.24 (0.62-2.51) |
0.54 |
||
| Two |
Age >50 years |
2.32 (1.78-3.04) |
<0.001 |
2.70 (2.15-3.39) <0.001 |
2.54 (2.06-3.12) |
<0.001 |
2.55 (2.07-3.14) |
<0.001 |
|
| Hypertension |
1.09 (0.80-1.50) |
0.58 |
1.14 (0.87-1.49) 0.36 |
0.99 (0.78-1.27) |
0.96 |
1.00 (0.78-1.28) |
0.99 |
||
| Diabetes | 0.92 (0.53-1.61) | 0.78 | 0.73 (0.43-1.23) 0.24 | 1.14 (0.67-1.95) | 0.62 | 0.98 (0.64-1.51) | 0.93 | ||
RP definition A: First eGFR >90; average slope during follow-up ≥5 per year; absolute decline ≥5 in two consecutive years; last eGFR <90.
RP definition B: First eGFR >90; absolute decline ≥5 in all years of follow-up; last eGFR <90.
$Results from multivariable logistic regression analysis.
*Insufficient numbers experiencing RP with this definition.