Table 2.

Values of EC50 to phenylephrine obtained from aortic rings with and without endothelium from adult male rats exposed or not to chronic stress or ethanol, alone or in combination

	Control EC50 (x10-7 M)	Stress EC50 (x10-7 M)	Ethanol EC50 (x10-7 M)	Stress/Ehanol EC50 (x10-7 M)
With endothelium	1.58 ± 0.15 (09)	2.25 ± 0.12 (09)	1.14 ± 0.10 (09)	1.79 ± 0.10 (09)
Without endothelium	0.88 ± 0.09* (09)	0.67 ± 0.08* (09)	0.80 ± 0.04* (09)	1.10 ± 0.07* (09)

Control: received water “ad libitum”; ethanol: received ethanol solution 20% instead of drinking water; stress: immobilization in a metallic containment tube (1 hour/day, 5 days/week for 6 weeks); chronic stress/ethanol: submitted to immobilization stress and exposed to 20% ethanol. Data expressed as mean ± SEM and, between parentheses, the number of independent determinations.

^*P < 0.05 in relation to the respective aorta with endothelium.