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. Author manuscript; available in PMC: 2014 Dec 1.
Published in final edited form as: Toxicol Appl Pharmacol. 2013 Oct 3;273(2):345–354. doi: 10.1016/j.taap.2013.09.026

Figure 2. SRT1720-induced deacetylation of PGC-1α after I/R.

Figure 2

(A) PGC-1α protein in the renal cortex at 72 h and 144 h after I/R by immunoblot analysis. (B) Nuclear PGC-1α from the renal cortex at 144 h after I/R by immunoblot analysis. (C) Acetylation of PGC-1α at 72 h and 144 h after I/R by immunoprecipitation with an anti-acetylated-lysine antibody, followed by immunoblot analysis of PGC-1α, with densitometric quantification of (C) at the 144 h time point in the graph to the right (n = 3). Asterisk (*) indicates data are significantly different from V group, and pound sign (#) indicates IRS was significantly different from the IRV group (ANOVA followed by Newman-Keuls, p<0.05).