TABLE II.

Total GPP130 fluorescence across all cells identified via Draq5 nuclear DNA staining in the dorsal striatum of control and Mn exposed rats, percent of all cells identified that were GPP130-positive (see text for defined positive fluorescence threshold limits), and total GPP130 fluorescence of GPP130-positive cells, all quantified at ×63 magnification

Treatment	Total fluorescence, all cellsa	% of GPP-positive cells	Total fluorescence, GPP-positive cells
Control	100±42	100±88	100±94
Mn	53±31**	23±55**	36±69b

Data expressed as percent of control group animals (see text for details).

Data are mean±SD, based on 10 fields per brain region (slice) from one representative brain slice/animal/treatment.

Asterisks indicate significantly different from paired control (*P<0.05; **P<0.001, t-test).