A. Activation in a region of the putamen (−15, 6, 3, Z = 3.59, P < 0.05 FDR corrected) during appetizing food - unappetizing food was negatively related to predicted values of future weight gain for participants with the A1 allele, but positively related to predicted values of future weight gain for participants without the A1 allele. B. Activation in the lateral OFC (36, 27, −15, Z = 3.27, P < 0.05 FDR corrected) during appetizing food – unappetizing food was negatively related to predicted values of future weight gain for participants with the A1 allele, but positively related to predicted values of future weight gain for participants without the A1 allele.