Table 2.
Comparison between the gene expression in colon tissues from control and HIV/HCV-infected patients
| Functions | HIV/HCV compared with controls* Gene family |
p Value | Number of genes involved |
|---|---|---|---|
| Molecular function | Receptor binding | 2.34E-08 | 30 |
| Extracellular matrix structural constituent | 4.16E-08 | 9 | |
| Collagen binding | 5.39E-06 | 6 | |
| Polysaccharide binding | 3.95E-05 | 9 | |
| Pattern binding | 3.95E-05 | 9 | |
| Biological process | Extracellular matrix organisation | 1.18E-11 | 14 |
| Cell adhesion | 1.39E-10 | 30 | |
| Biological adhesion | 1.39E-10 | 30 | |
| Extracellular structure organisation | 2.42E-10 | 16 | |
| Response to wounding | 1.10E-09 | 31 | |
| Cellular component | Extracellular region part | 3.47E-20 | 48 |
| Extracellular space | 4.93E-17 | 39 | |
| Proteinaceous extracellular matrix | 7.33E-15 | 24 | |
| Extracellular matrix | 3.17E-14 | 25 | |
| Extracellular matrix part | 2.19E-11 | 14 | |
| Pathways | ECM-receptor interaction | 2.14E-10 | 12 |
| Focal adhesion | 8.54E-08 | 14 | |
| Genes involved in integrin cell surface interactions | 4.64E-06 | 8 | |
| Syndecan-2-mediated signalling events | 3.89E-05 | 5 | |
| Integrin signalling pathway | 1.05E-04 | 9 | |
| Gene family | Histocompatibility complex genes | 6.31E-04 | 3 |
| Chemokine ligands | 5.84E-03 | 2 | |
| CD molecules | 2.28E-02 | 4 |
*
Date were presented as group of genes according to their functions, and the numbers of genes in each group.