. Author manuscript; available in PMC: 2014 Apr 15.

Published in final edited form as: Science. 2008 Sep 25;322(5903):945–949. doi: 10.1126/science.1162494

Table 1.

Derivation and characterization of Adeno-iPS cells from different cell types

Source of cells	Oct4^ind	GFP	Sex	MOI	iPS lines (2n/4n)	Efficiency (iPS/input)	ES	TF	PC	GL
Fetal liver	Yes	No	F	20–50	6/0	0.0012%	Yes	Yes	ND	ND
Fetal liver	Yes	Sox2	M	20–50	2/1	0.0006%	Yes	Yes	Yes	ND
Fibroblast	Yes	Oct4	M	50–250	1/0	<0.0001%	Yes	Yes	Yes	Yes
Hepatocyte	No	Oct4	F	1–4	1/2	0.0005%	Yes	Yes	Yes	ND

Oct4^ind = Oct4^ind allele present

GFP = GFP reporter gene present

ES = expression of ES cell markers (SSEA1 and Oct4 or Sox2)

TF = teratoma formation

PC = postnatal chimeras

GL = germline transmission