Table 1.
Comparison of genes that exhibited Semax-induced alteration of expression levels after pMCAO
| Gene symbol |
Ischemia + semax 3 h |
Ischemia + semax 24 h |
ENTREZ GENE_ID | ||
|---|---|---|---|---|---|
| lg (Ratio) | P-value | lg (Ratio) | P-value | ||
|
RGD1562905 |
0.58 |
1.1E-04 |
−0.53 |
2.1E-34 |
292539 |
|
Adamts1 |
0.34 |
5.2E-11 |
−0.25 |
7.5E-09 |
79252 |
|
Zfp36 |
0.24 |
5.5E-03 |
−0.16 |
2.0E-04 |
79426 |
|
Ptprcap |
−0.28 |
2.3E-03 |
0.29 |
9.8E-08 |
499300 |
|
Ccdc53 |
−0.29 |
1.3E-06 |
0.18 |
4.6E-03 |
299707 |
|
RT1-Ba |
−0.29 |
3.1E-07 |
0.36 |
1.5E-15 |
309621 |
|
Cd74 |
−0.30 |
1.6E-09 |
0.21 |
5.3E-06 |
25599 |
|
RT1-A1 |
−0.30 |
7.6E-10 |
0.29 |
2.8E-11 |
24973 |
|
H2-Ea |
−0.31 |
4.1E-10 |
0.15 |
7.3E-04 |
294269 |
| Igh-1a | −0.79 | 2.6E-30 | 0.47 | 3.5E-26 | 299352 |
The table shows the genes that exhibited significantly changed expression under Semax treatment at both time points (3 and 24 h). The logarithmic transformed value visually represents the symmetric changes in expression levels: negative value indicates decrease and positive value – increase of the gene expression level. The cut-off of gene-expression changes was 1.40. Ratio – relative expression level.