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. Author manuscript; available in PMC: 2015 Mar 10.
Published in final edited form as: Brain Res. 2014 Jan 16;1551:45–58. doi: 10.1016/j.brainres.2014.01.013

Figure 6. p38 MAPK inactivation attenuates wound healing in primary astrocyte cultures.

Figure 6

A. Depicts are representative microscopic images of Calcein AM labeled astrocytes at day 0, 1, and 2 after scratch injury. SB239063, a p38 inhibitor, substantially slows down the healing process. B. Quantitative analysis of wound healing assay demonstrated that SB239063 significantly inhibits wound healing in primary astrocyte cultures. C. Quantitative analysis of wound healing assay in primary astrocyte cultures derived from wild type and GFAP/p38 knockout mice demonstrated that p38 knockout significantly inhibit wound healing. *** p<0.001 vs. day 1 WT, # p<0.05 vs. day 2 WT.