Figure 3. DNase activity of individual IgGs from several CSFs (A) and sera (B) of MS patients in the cleavage of scDNA.

The reaction mixtures were incubated with the IgGs from CSFs (0.003 mg/ml) and sera (0.2 mg/ml) for 2 h at 37°C. Lane C in each group of IgGs corresponds to scDNA incubated without Abs mark the positions of supercoiled (scDNA) and relax DNA plasmid (relDNA) are shown.