Table 3. Relative DNase activity of total proteins and IgGs from CSF and sera of patients with MS.*.
| Number of patient | Relative specific DNase activity of total proteins; pmole DNA/1 mg of protein/1 h | Relative DNase activity of total proteins; pmole DNA/1 ml of initial solution/1 h | Relative specific DNase activity of IgGs; pmole DNA/1 mg of Ab/1 h | ||||||
| CSF (7) | Serum (8) | CSF (9) | Serum (10) | CSF (11) | Serum (12) | ||||
| 1 | 118 | 0.41 | 64 | 24 | 528.9 | 17.5 | |||
| 2 | 70 | 0.38 | 23 | 24 | 716 | 5.2 | |||
| 3 | 263 | 0.33 | 69 | 23 | 778.9 | 3.6 | |||
| 4 | 118 | 0.43 | 62 | 27 | nd | ndµ | |||
| 5 | 25 | 0.72 | 16 | 34 | 564.6 | 10.5 | |||
| 6 | 62 | 0.26 | 36 | 17 | nd | nd | |||
| 7 | 55 | 0.43 | 31 | 28 | 544.2 | 13.1 | |||
| 8 | 25 | 0.46 | 14 | 34 | 129.3 | 17.6 | |||
| 9 | 78 | 0.47 | 29 | 34 | 117.3 | 17,0 | |||
| 10 | 44 | 0.75 | 17 | 45 | 210.9 | 7.8 | |||
| 11 | 133 | 0.61 | 56 | 35 | 1190.5 | 20.8 | |||
| 12 | 100 | 0.33 | 53 | 25 | 928.6 | 12.2 | |||
| 13 | 244 | 0.76 | 95 | 44 | 171.8 | 3.9 | |||
| 14 | 78 | 0.88 | 51 | 51 | 629.3 | 11.6 | |||
| 15 | 100 | 0.43 | 44 | 20 | 552.7 | 10.4 | |||
| Average value** | 101±50 | 0.51±0.16 | 41.3±18.8 | 31±8 | 543.3±239.7 | 11.2±4.3 | |||
| Ratio of the values | 198.0 | 1.3 | 48.5 | ||||||
| Coefficient correlation | −0.05 (p<0.05) | 0.03 (p<0.05) | 0.26 (p<0.05) | ||||||
| Coefficients of correlation between different values corresponding to column numbers of Tables 2 and 3 | |||||||||
| Numbers | 1 and 7 | 2 and 8 | 3 and 11 | 4 and 12 | 5 and 11 | 6 and 2 | |||
| Coefficient correlation | +0.61 (p<0.05) | −0.49 (p<0.05) | +0.16 (p<0.05) | +0.58 (p<0.05) | +0.11 (p<0.05) | +0.51 (p<0.05) | |||
*For each value, a mean of three measurements is reported; the error of the determination of values did not exceed 7–10%.
**Average values are reported as mean ± S.E.
µ
No determined.