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. 2014 Apr 15;9(4):e93634. doi: 10.1371/journal.pone.0093634

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© 2014 Abreu et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Animals were euthanized on day 21 post infection (p.i.) and plasma and urine samples were collected for analysis of renal function. Analysis of control_21d, control+BSA _21d, control+treated+BSA_21d, infected+treated_21d, and infected+treated+BSA_21d: (A) serum creatinine, (B) blood urea nitrogen (BUN); (C) BUN/serum creatinine ratio; (D) creatinine clearance (CCr); and (E) urinary protein/urinary creatinine (UPC) ratio. *Statistically significant compared with control_21d. #Statistically significant compared with infected+treated _21d (P<0.05).