Figure 7. Glomerular cell number decreases in mice subjected to a second kidney insult.

Animals were euthanized on day 21 post infection (p.i.), perfused, and the kidneys were collected for histologic analysis. The number of glomerular cells in the renal cortex was visualized using periodic acid−Schiff. Representative photomicrographs of (A) control_21d, (B) control+BSA _21d, (C) control+treated+BSA _21d, (D) infected+treated _21d, and (E) infected+treated+BSA _21d (n = 6 per group). Bar = 40 µm. The number of glomerular cells is quantified in (F). The results are expressed as means ± standard error. *Statistically significant compared with control_21d. #Statistically significant compared with infected+treated _21d (P<0.05).