Figure 1. miR-338 is down-regulated in gastric cancer tissues and cell lines.

(A) The expression levels of mature miR-338 in gastric cancer (n = 41) and adjacent normal mucosa tissues (n = 24) were determined using quantitative PCR. Both the gastric cancer and adjacent normal mucosa samples were fresh dissected. The expression level of mature miR-338 in the gastric cancer tissues was significantly lower than in the adjacent normal mucosa tissues. The data from the cell lines and the human samples are shown separately. * p<0.01(B)miR-338 was decreased in the gastric cancer cell lines (SGC7901, HGC27, AGS, MKN45 and N87) compared with the normal gastric mucosa cell line (GES1). The data represent the means± s.d. (n = 3) of the cell lines. ** p<0.01.