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. 2014 Apr 15;9(4):e94163. doi: 10.1371/journal.pone.0094163

Table 1. Demographic characteristics according to endoscopic BE and pathological BE in the training cohort*.

CLE IM≥2 cm
BE Normal P BE Normal P
N 182 1421 69 1534
Age (yrs) 58.1 (12.7) 51.7 (14.2) <0.001 60.9 (11.9) 52.0 (14.1) <0.001
BMI (kg/m2) 27.1 (4.2) 26.6 (5.1) 0.21 27.5 (4.5) 26.6 (5.1) 0.16
Ethnic
Caucasian 128 (11.4%) 996 (88.6%) 0.19 51 (4.5%) 1,073 (95.5%) 0.30
Bangladeshi 32 (13.9%) 198 (86.1%) 11 (4.8%) 219 (95.2%)
Other 6 (6.7%) 83 (93.3%) 1 (1.1%) 88 (98.9%)
Sex
Male 118 (15.1%) 665 (84.9%) <0.001 46 (5.9%) 737 (94.1%) 0.003
Female 62 (7.6%) 756 (92.4%) 23 (2.8%) 795 (97.2%)
Education
High school or less 128 (12.2%) 917 (87.8%) 0.21 50 (4.8%) 995 (95.2%) 0.51
College 29 (11.4%) 225 (88.6%) 10 (3.9%) 244 (96.1%)
University or higher 16 (7.3%) 203 (92.7%) 8 (3.7%) 211 (96.3%)
Other 3 (9.4%) 30 (90.6%) 0 (0%) 33 (100.0%)
Smoking
Never 59 (10.6%) 500 (89.4%) 0.05 18 (3.2%) 541 (96.8%) 0.05
Former 57 (12.9%) 385 (87.1%) 25 (5.7%) 417 (94.3%)
Current 26 (7.5%) 322 (92.5%) 9 (2.6%) 339 (97.4%)
Alcohol drinking
Non-drinker 18 (8.8%) 186 (91.2%) 0.35 9 (4.4%) 195 (95.6%) 0.74
Drinker 127 (11.0%) 1,024 (89.0%) 45 (3.9%) 1,106 (96.1%)
Family history of BE
Yes 3 (16.7%) 15 (83.3%) 0.45 2 (11.1%) 16 (88.9%) 0.18
No 179 (11.3%) 1,406 (88.7%) 67 (4.2%) 1,518 (95.8%)
Family history of EAC
Yes 8 (12.7%) 55 (87.3%) 0.73 2 (3.2%) 61 (96.8%) 1.0
No 174 (11.3%) 1366 (88.7%) 67 (4.4%) 1,473 (95.6%)
Heartburn
Never 25 (8.4%) 271 (91.6%) 0.007 9 (3.0%) 287 (97.0%) 0.04
Sometimes 14 (8.1%) 159 (91.9%) 3 (1.7%) 170 (98.3%)
Often 46 (10.1%) 410 (89.9%) 18 (3.9%) 438 (96.1%)
Daily 60 (14.6%) 351 (85.4%) 23 (5.6%) 388 (94.4%)
Acid flux
Never 37 (9.1%) 371(90.9%) 0.009 12 (2.9%) 396 (97.1%) 0.07
Sometimes 17 (6.3%) 253 (93.7%) 8 (3.0%) 262 (97.0%)
Often 57 (13.1%) 378 (86.9%) 20 (4.6%) 415 (95.4%)
Daily 31 (14.0%) 190 (86.0%) 12 (5.4%) 209 (94.6%)
Chest Pain
Never 70 (13.0%) 467 (87.0%) 0.03 29 (5.4%) 508 (94.6%) 0.07
Mild 31 (9.4%) 299 (90.6%) 10 (3.0%) 320 (97.0%)
Moderate 35 (10.3%) 305 (89.7%) 10 (2.9%) 330 (97.1%)
Severe 8 (6.3%) 120 (93.8%) 4 (3.1%) 124 (96.9%)
Being woken at night by symptoms
No 86 (11.6%) 654 (88.4%) 0.75 32 (4.3%) 708 (95.7%) 0.97
Yes 96 (11.1%) 767 (88.9%) 37 (4.3%) 826 (95.7%)
Abdominal pain
No 59 (16.4%) 301 (83.6%) <0.001 28 (7.8%) 332 (92.2%) <0.001
Yes 85 (8.7%) 895 (91.3%) 25 (2.6%) 955 (97.4%)
Anti-reflux medication
No 47 (7.3%) 597 (92.7%) <0.001 14 (2.2%) 630 (97.8%) <0.001
Yes 88 (14.3%) 528 (85.7%) 38 (6.2%) 578 (93.8%)

*Data shown are mean (SD) for continuous variables and number (percentage) for categorical variables

P for trend test.