Table 1. Long-term fructose bingeing did not alter D1R or D2R number.
D1R [3H]-SCH23390 | D2R [3H]-Spiperone | |||
Bmax | Kd | Bmax | Kd | |
(fmol/mg protein) | (pM) | (fmol/mg protein) | (pM) | |
Nucleus accumbens shell | ||||
Chow | 223±4 | 430±42 | 117±4 | 136±13 |
4% fructose | 222±4 | 424±42 | 114±2 | 115±15 |
8% fructose | 227±5 | 477±49 | 117±7 | 120±15 |
12% fructose | 217±5 | 422±53 | 119±7 | 132±32 |
Nucleus accumbens core | ||||
Chow | 189±6 | 417±63 | 97±8 | 140±16 |
4% fructose | 194±6 | 420±61 | 93±5 | 128±22 |
8% fructose | 202±5 | 421±45 | 104±9 | 128±13 |
12% fructose | 188±6 | 432±68 | 108±6 | 165±23 |
Dorsal striatum | ||||
Chow | 225±4 | 439±35 | 175±6 | 163±18 |
4% fructose | 220±4 | 408±36 | 170±7 | 135±25 |
8% fructose | 223±4 | 438±39 | 169±11 | 148±24 |
12% fructose | 219±6 | 425±51 | 166±7 | 148±21 |
Mean values ± SEM, n = 8/group.