Table 1. Characteristics of patients included and univariate analysis of routine indicators according to hepatic inflammation grade.
| Variable | Total patients (n = 120) | G0/G1 (n = 17) | G2 (n = 67) | G3/G4 (n = 36) | P value |
| Age, yrs | 51.33±7.33 | 50.41±8.42 | 50.88±7.07 | 52.58±7.33 | 0.36 |
| Male, n (%) | 57(47.50) | 3 (17.65) | 35 (52.24) | 19 (52.78) | 0.03 |
| ALT (U/L) | 60.42±70.88 | 29.34±17.66 | 48.37±33.78 | 97.52±112.35 | <0.001 |
| AST (U/L) | 47.94±44.30 | 27.49±10.18 | 40.33±18.78 | 71.76±71.16 | <0.001 |
| TBIL (µmol/L) | 16.51±7.25 | 13.40±4.47 | 17.06±7.42 | 16.96±7.75 | 0.13 |
| DBIL (µmol/L) | 3.26±1.36 | 2.89±1.14 | 3.23±1.23 | 3.50±1.65 | 0.43 |
| TP (g/L) | 70.93±4.95 | 69.84±3.65 | 71.23±5.27 | 70.89±4.89 | 0.59 |
| Albumin (g/L) | 43.21±2.36 | 44.34±1.84 | 43.19±2.38 | 42.72±2.43 | 0.06 |
| Globulin (g/L) | 29.19±17.29 | 26.08±3.57 | 30.50±22.84 | 28.23±4.19 | 0.09 |
| GGT (U/L) | 22.04±16.50 | 16.49±10.89 | 18.00±8.00 | 32.17±24.46 | <0.001 |
| ALP (U/L) | 76.29±20.91 | 75.35±18.52 | 72.57±17.25 | 83.64±26.19 | 0.11 |
| TBA (µmol/L) | 11.24±46.76 | 4.57±2.75 | 13.70±62.44 | 9.80±6.61 | 0.004 |
| Cholinesterase (U/L) | 6957.09±1442.44 | 7541.44±2140.99 | 6882.53±1350.68 | 6819.92±1158.74 | 0.09 |
| PTA (%) | 92.41±9.11 | 98.47±6.30 | 92.96±9.39 | 88.50±7.99 | <0.001 |
Data are means ± SD or number of patients (%).
P values are acquired by one-way analysis of variance or the nonparametric Kruskal-Wallis test for continuous variables depending on the data distribution, and by Pearson χ2 for categoric variables.
ALT: alanine aminotransferase; AST: aspartate aminotransferase; TBIL: total bilirubin; DBIL: direct bilirubin; TP: total protein; GGT: γ-glutamyl transpeptidase; ALP, alkaline phosphatase; TBA: total bile acid; PTA: prothrombin activity.