Skip to main content

View full-text article in PMC

. 2014 Apr 15;9(4):e95303. doi: 10.1371/journal.pone.0095303

Table 2. Associations between FISH status and patient characteristics.

	SOX2					PIK3CA					FGFR1					BRF2
	(N = 445)					(N = 435)					(N = 445)					(N = 435)
	−		+			−		+			−		+			−		+
	n	%	n	%	P value	n	%	n	%	P value	n	%	n	%	P value	n	%	n	%	P value
Total	340	76.4	105	23.6		308	70.8	127	29.2		371	83.4	74	16.6		370	85.1	65	14.9
Sex
Male	273	74.0	96	26.0	0.012	243	67.7	116	32.3	0.003	305	82.7	64	17.3	0.469	300	83.6	59	16.4	0.085
Female	67	88.2	9	11.8		65	85.5	11	14.5		66	86.8	10	13.2		70	92.1	6	7.9
Smoking History
Never	37	92.5	3	7.5	0.010	35	89.7	4	10.3	0.005	37	92.5	3	7.5	0.121	38	97.4	1	2.6	0.018
Former + Current	296	74.4	102	25.6		265	68.3	123	31.7		327	82.2	71	17.8		324	83.5	64	16.5
Histology
SCC	69	50.0	69	50.0	<0.001^a	55	41.3	78	58.7	<0.001^a	99	71.7	39	28.3	<0.001^a	95	71.4	38	28.6	<0.001^a
Adenocarcinoma	217	89.3	26	10.7		199	84.0	38	16.0		215	88.5	28	11.5		215	90.3	23	9.7
Other	54	84.4	10	15.6		54	83.1	11	16.9		57	89.1	7	10.9		60	93.8	4	6.2
Stage
I–II	200	75.5	65	24.5	0.654	179	69.4	79	30.6	0.495	222	83.8	43	16.2	0.883	221	85.7	37	14.3	0.773
III–IV	140	77.8	40	22.2		129	72.9	48	27.1		149	82.8	31	17.2		149	84.2	28	15.8
Grade
I–II	226	79.0	60	21.0	0.089	207	74.2	72	25.8	0.040	241	84.3	45	15.7	0.545	239	85.4	41	14.6	0.881
III	112	71.3	45	28.7		99	64.3	55	35.7		128	81.5	29	18.5		129	84.3	24	15.7

^a

SCC vs non-squamous histology.

Abbreviation: SCC = squamous cell carcinoma.