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. 2014 Apr 15;9(4):e95329. doi: 10.1371/journal.pone.0095329

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© 2014 Tsukiyama, Ohinata

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) Teratoma formation of ESC-INTPSCs. (B) Differentiation of ESC-INTPSCs into the three germ layers. Left panel shows a keratinocyte-like structure; center panel shows a cartilage-like structure; and right panel shows an intestinal epithelium–like structure. (C) Contributions of ESCs and ESC-INTPSCs to chimeras.