. Author manuscript; available in PMC: 2015 May 1.

Published in final edited form as: Hum Genet. 2013 Nov 20;133(5):575–586. doi: 10.1007/s00439-013-1398-9

Table 4.

Meta-analysis results of SNPs in CHRNA2 and CHRNA6 with ND in both the discovery and replication samples

Gene	dbSNP ID	Allele	African American	European American	AA + EA Samples
CHRNA2	rs2292976	A	0.00325^d	0.195^d	0.00530^d
	rs3735757	G	0.404^r	0.011^r	0.0252^r
	rs891398	T	0.0187^a	0.402^a	0.0443^a
	rs2472553	T	0.554^r	0.00258^r	0.0108^r
CHRNA6	rs9298628	C	0.998^r	0.000592^r	0.00498^r
	rs892413	C	0.120^r	0.00290^r	0.00311^r
	rs2217732	A	0.981^r	0.000505^r	0.00426^r

Notes: 1) For each SNP, meta-analysis was performed on only one genetic model, which was selected on the basis of the association analysis result for both the discovery and the replication samples; 2) I² was calculated only for the replication case-control samples with the METAL program.