Table 1. Comparisons of the demographic features of MS patients according to the CSF IgG abnormality status.
CSF IgG abnormality (+) (n = 59) | CSF IgG abnormality (−) (n = 35) | P value | |
Male:female | 18∶41 | 15∶20 | 0.2669 |
Age at onset (years)a | 30.54±12.12 | 34.06±15.70 | 0.4157 |
Disease duration (years)a | 10.48±8.24 | 10.29±8.45 | 0.7899 |
EDSS scorea | 2.74±1.92 | 2.83±1.84 | 0.6420 |
Annualized relapse ratea | 0.58±0.60 | 0.87±0.90 | 0.0946 |
Progression indexa | 0.39±0.39 | 0.90±2.00 | 0.4740 |
Barkhof criteriab | 46/58 (79.3%) | 16/34 (47.1%) | 0.0025 |
OSMS with short spinal cord lesionsc | 13/59 (22.0%) | 11/35 (31.4%) | 0.3366 |
Values represent the mean ± SD.
Brain MRI lesions meeting the Barkhof criteria [34].
Opticospinal form of MS with short spinal cord lesions extending less than three vertebral segments.
CSF, cerebrospinal fluid; EDSS, Kurtzke's Expanded Disability Status Scale; MS, multiple sclerosis.