Figure 7. Proviral effect of LC3 lipidation.

MA104 cells were transfected with the indicated siRNAs and at 48(OSU strain; MOI, 5) for 13 h (A, B) or 24 h (C). A) Western blot of cellular extracts. B) Quantification of the accumulation of viroplasms per cell. C) Viral titers obtained from each condition. The results are expressed as mean ±SEM from at least three independent samples for each experimental condition, and in B data were normalized as percentage from the control. In all figures: siNT, control non-targeting siRNA. t-test, **, p<0.01.