The uptake of 18F-TPP was decreased as the extracellular potassium
concentration increased. At the highest potassium concentration of 172.8
μM, the uptake was the lowest, while at the lowest potassium
concentration of 10.8 μM, the uptake was at the highest. An inverse
linear correlation between the uptake and extracellular potassium concentration
(slope: 0.62+/− 0.78; correlation coefficient:
r=0.936+/− 0.11) was found (Fig. 2 A: ANOVA, *
vs. **: P<0.05; **
P>0.05). Gradually increased concentrations of CCCP lead
to decreased uptakes of 18F-TPP, which quickly reached a trough at
CCCP concentration of 5μm (Fig. 2 B: ANOVA, *
P>0.05).