Table 4.
Funding source, number of centers, and locations
| Subset Comparison | ||||
|---|---|---|---|---|
| Trial Attribute | Nephrology (n=1054) | Cardiologya (n=2264) | P-value | Otherb (n=37,652) |
| Fundingc | 0.3 | |||
| Industry | 465 (44.1) | 950 (42.0) | 17,422 (46.3) | |
| NIH | 35 (3.3) | 95 (4.2) | 3408 (9.1) | |
| Other | 554 (52.6) | 1219 (53.8) | 16,822 (44.7) | |
| 1 sponsor or collaborator | 711 (67.5) | 1455 (64.3) | 0.07 | 25,155 (66.8) |
| Sponsor; no. of centers classification | n=996 | n=2096 | 0.1 | n=34,428 |
| Industry funded; single center | 188 (18.9) | 350 (16.7) | 7485 (21.7) | |
| Industry funded; multicenter | 248 (24.9) | 507 (24.2) | 7896 (22.9) | |
| NIH funded; single center | 19 (1.9) | 59 (2.8) | 2050 (6.0) | |
| NIH funded; multicenter | 14 (1.4) | 35 (1.7) | 1077 (3.1) | |
| Other; single center | 445 (44.7) | 917 (43.8) | 13,275 (38.6) | |
| Other; multicenter | 82 (8.2) | 228 (10.9) | 2645 (7.7) | |
| Location | n=996 | n=2096 | 0.008 | n=34,428 |
| US only | 375 (37.7) | 673 (32.1) | 16,031 (46.6) | |
| Foreign only | 566 (56.8) | 1283 (61.2) | 16,147 (46.9) | |
| Both US and foreign | 55 (5.5) | 140 (6.7) | 2250 (6.5) | |
Note: Unless otherwise indicated, values are given as number (percentage). Each study has one lead sponsor, but a study may have several collaborators. Chi-squared test used for class variables, Wilcoxon rank sum test used for continuous variables.
a
Excludes studies classified as both nephrology and cardiology.
b
Excludes studies classified as nephrology or cardiology.
c
Derived from lead sponsor and collaborator fields.
Abbreviations: NIH, National Institutes of Health; US, United States.