Table 1.
Characteristics of patients included in regression and progression models (n = 243).
| Variable | No. (IQR or %) |
|---|---|
|
| |
| Age at reflex FISH, yr, median | 71 (64, 78) |
|
| |
| Male | 202 (83) |
|
| |
| T stage | |
| Ta | 106 (44) |
| T1 | 91 (37) |
| Tis | 46 (19) |
|
| |
| Carcinoma in situ | 126 (52) |
|
| |
| History of UTUC | 10 (4) |
|
| |
| Tumor grade | |
| Low | 47 (19) |
| High | 196 (81) |
|
| |
| IVT prior to FISH | 155 (64) |
| BCG onlya | 127 (52) |
| BCG+otherb | 18 (8) |
| Mitomycin-C only | 10 (4) |
|
| |
| FISH result | |
| Negative | 76 (31) |
| Uninformative | 67 (28) |
| Positive | 100 (41) |
IQR = interquartile range; FISH = fluorescence in situ hybridization; UTUC = upper tract urothelial carcinoma; IVT = intravesical therapy; BCG = bacillus Calmette-Guérin.
a
Includes patients receiving induction BCG only or induction plus maintenance BCG.
b
Other agents include interferon (10 patients), thiotepa (4 patients), gemcitabine (3 patients), Adriamycin (1 patient)