Figure 3.
A: Hemodynamic waveforms from the same animal during intraaortic balloon pump (IABP) support demonstrated suprasytolic diastolic augmentation and afterload reduction (top panel). Rapid balloon deflation and the drop in end-diastolic blood pressure produced aortic, carotid, and left anterior descending (LAD) coronary artery flow reversal. Arrows indicate periods of flow reversal. Waveforms show 1:2 IABP support to illustrate that flow reversal is not present with unsupported beats. B: Aortic flow (AoF) reversal increased significantly during 1:1 IABP support. C: Carotid flow (CarotidF) reversal increased significantly during 1:1 IABP support. D: LAD flow (LADF) increased significantly during 1:1 IABP support. B–D: Flow reversal was not attenuated in any artery during 1:1 IABP therapy triggered with a low-fidelity (fluid-filled) catheter in the radial artery or a high-fidelity (micromanometer) catheter in the aorta. LV, left ventricular; *p<0.01 vs. baseline; †p<0.05 vs. LV failure.