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. Author manuscript; available in PMC: 2015 Jun 1.
Published in final edited form as: Mol Psychiatry. 2013 Oct 15;19(12):1284–1294. doi: 10.1038/mp.2013.135

Figure 3. Long-term pharmacological stimulation of ghrelin receptor activity in the amygdala enhances fear memory.

Figure 3

Rats were implanted with bilateral cannulae aimed at the basolateral amygdala (BLA). The arrow indicates the tip of the injector within a representative coronal brain section. Following recovery, intra-BLA infusions of either MK-0677 (MK-Inf: 5d) or aCSF (VEH-Inf: 5d) were administered daily for five consecutive days and, 24h following the final infusion, (a) auditory fear conditioning was administered. (b) Fear memory was assessed in a novel context 48h following fear conditioning. Brain illustration adapted from (88). All data are mean ±s.e.m. ** p<0.01 in planned comparisons.