Figure 1.
Tumor growth process in breast cancer bearing mice. Mice were inoculated with 4T1 cells and treated with dimethyl sulfoxide (DMSO) of various dose (0.25-1.0 mg/g) or normal saline (NS) for consecutive 10 days intraperitoneal injection Tumors volume was calculated as: L×S2×0.52. (A) Tumor growth curve. The tumor volume growth of experimental groups was inhibited (except for 0.25 mg/g) by a dose and time-dependent way. (B) Tumors were dissected 19 days after inoculation and weighed. Bars represent means±SD. Graph shows tumor weight of experimental groups (except for 0.25 mg/g) was decreased compared with control.
*p<0.03 vs. control; †p<0.05 vs. 0.5 mg/g group (n=5).