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. 2014 Apr 9;8:35. doi: 10.3389/fncir.2014.00035

Figure 6.

Figure 6

Model of larval olfactory pathway with feedback inhibition in the mushroom body. Single olfactory sensory neurons (OSNs) project to single antennal lobe (AL) glomeruli, from where single projection neurons (PNs) project mostly to single glomeruli in the mushroom body (MB) calyx. Odors normally activate multiple OSNs and hence multiple PNs and calyx glomeruli (two examples shown in orange and thick lines). If enough dendritic branches of an individual Kenyon cell (KC) are activated by inputs from multiple calyx glomeruli, the KC transmits signals to the MB lobes. The APL responds to KC activity in the MB lobes and transmits an inhibitory feedback signal (GABA) to the MB input region in the calyx. Adapted from Masuda-Nakagawa et al. (2009).