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The glucocorticoid receptor mechanism proposed for how environment-triggered epigenetic changes affect SCI recovery. The bold black lines indicate a negative process and the light gray lines indicate a positive process in our model. Arrows (→) indicate that a process is enabled, and bars (–|) indicate that a process is inhibited. The dotted line indicates a feedback loop. GR, glucocorticoid receptor; SCI, spinal cord injury.
