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. 2014 Apr 16;34(16):5454–5467. doi: 10.1523/JNEUROSCI.4350-13.2014

Table 2.

Optimization results for fitting the statistical power function (Eq. 8) to the experimental data pαn for all investigated α levels

α CEEα, AllExTT αparam, AllExTT μ0 μ1 σparam, AllExTT LSSAllExTT R2AllExTT
0.5 46.29 0.415 1.83 2.2 0.267 62.649 0.36
0.2 39.18 0.470 1.83 2.2 1.042 20.919 0.94
0.1 30.09 0.271 1.83 2.2 0.691 10.824 0.98
0.05 24.73 0.166 1.83 2.2 0.631 8.583 0.98
0.02 21.39 0.090 1.83 2.19 0.612 6.378 0.99
0.01 19.01 0.060 1.83 2.2 0.582 4.222 0.99
5 × 10−3 18.13 0.040 1.83 2.2 0.572 3.806 0.99
2 × 10−3 17.43 0.032 1.83 2.2 0.606 4.147 0.99
1 × 10−3 16.74 0.026 1.83 2.2 0.617 3.488 0.99
5 × 10−4 14.70 0.020 1.83 2.2 0.578 2.834 0.99
2 × 10−4 11.63 0.014 1.83 2.2 0.508 3.092 0.99
1 × 10−4 10.73 0.012 1.83 2.2 0.507 2.555 0.99
5 × 10−5 10.20 0.009 1.83 2.2 0.487 3.307 0.98
2 × 10−5 9.45 0.010 1.83 2.2 0.506 2.507 0.98
1 × 10−5 8.85 0.009 1.83 2.2 0.489 2.952 0.98
abs 8.56 0.007 1.83 2.2 0.470 3.056 0.98
α CEEα, AllEx αparam, AllEx μ0 μ1 σparam, AllEx LSSAllEx R2AllEx
0.5 57.02 0.7 1.83 2.2 0.804 4.706 0.97
0.2 37.85 0.49 1.83 2.2 0.913 5.264 0.98
0.1 25.53 0.35 1.83 2.2 0.864 2.539 0.99
0.05 17.00 0.22 1.83 2.2 0.741 1.858 0.99
0.02 10.94 0.11 1.83 2.19 0.649 1.577 0.99
0.01 8.06 0.06 1.83 2.2 0.577 1.383 0.98
5 × 10−3 8.02 0.06 1.83 2.2 0.573 1.739 0.98
2 × 10−3 5.34 0.02 1.83 2.2 0.583 0.478 0.99
1 × 10−3 4.76 0.02 1.83 2.2 0.629 0.214 0.99
5 × 10−4 4.21 0.02 1.83 2.2 0.637 0.189 0.99
2 × 10−4 3.27 0.02 1.83 2.2 0.603 0.102 0.99
1 × 10−4 2.65 0.02 1.83 2.2 0.603 0.056 0.99
5 × 10−5 2.53 0.01 1.83 2.2 0.554 0.063 0.99
2 × 10−5 2.18 0.01 1.83 2.2 0.529 0.083 0.99
1 × 10−5 2.15 0.01 1.83 2.2 0.535 0.076 0.99
abs 1.97 0 1.83 2.2 0.455 0.112 0.99

Top, The table shows the optimization results for all 16 α levels using simulated annealing for fitting the data pαn normalized by the number of excitatory neuron pairs per tetrode (NAllExTT). The left column represents the significance thresholds (α) that were applied to count the number of significant cross-correlations. The parameter CEEα,AllExTT (the asymptotic detection probability of excitatory connections pαn), αparam,AllExTT as well as σparam,AllExTT were optimized using simulated annealing. μ0 and μ1 were estimated from the data; μ0 is the mean of the jittered cross-correlations of all EE pairs. μ1 is the mean of the peaks within the window [−4;4] of all significant EE cross-correlations. LSS (least sum of squares)AllExTT shows the smallest LSS that was used to select the best fit out of the 1000 optimization trials. R2AllExTT provides a measure for the goodness of the optimization result. Bottom, The table shows the simulated annealing optimization results for all 16 α levels for fitting the data normalized by the total number of excitatory neuron pairs (NAllEx). CEEα,AllEx, αparam,AllEx, and σparam,AllEx were optimized using simulated annealing. The columns for α, μ0, μ1, LSS, and RAllEx2 are as described in the top.