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Effect of saquinavir (SQ) and lopinavir (LPV) on Plasmodium berghei invasion. Sporozoites were preincubated with the indicated concentrations of drug and then added to hepatocytes in the continued presence of the drug for a 1-h period. Extracellular sporozoites and total sporozoites per field were counted in 50 fields per well, and the percent invasion was then calculated. *P<.05 (statistically significant difference between the treated group and the control group).
