Figure 3.

B and T lymphocyte attenuator (BTLA) down-regulation in CD4⁺ T-cell subsets in human immunodeficiency virus (HIV)-1–infected individuals. A, Representative BTLA expressions on CD4⁺ T-cell subsets from a healthy subject and an HIV-1-infected individual. The percentages of each CD4⁺ T-cell population are shown in each quadrant (left panel). The BTLA percentages in each CD4⁺ T-cell population are shown as histograms (right panel). B, Statistical analysis of the BTLA expression levels in CD4⁺ T-cell subsets in the different study groups. *P < .05. Multiple comparisons were made using the Kruskal-Wallis H nonparametric test among the different groups. The Mann-Whitney U test was used to compare data from 2 different groups. Tn, naive T cells; Tcm, central memory T cells; Tem, effector memory T cells.