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Possible mechanisms for the oxidative cleavage of resveratrol. Shown are two proposed mechanisms for oxidative cleavage with CCO enzymes. A dioxygenase mechanism results in both aldehyde cleavage products labeled with isotopic 18O when the reactions are performed in an 18O atmosphere. The monooxygenase mechanism results in a single isotopic 18O labeled cleavage product when reactions are performed in an 18O atmosphere.
