Table 2.
Risk of Discontinuation or Change in Treatmet | |||||
---|---|---|---|---|---|
Treatment | Number of episodes of use | Number of events | Median duration on treatment (IQR) | Unadjusted Hazard Ratio (95% confidence interval) | Adjusted Hazard Ratio (95% confidence interval) |
Fludrocortisone | 1103 | 329 | 254 (119–783) | Reference | Reference |
Midodrine | 664 | 210 | 259 (119–807) | 1.04 (0.89, 1.24) | 1.07 (0.90, 1.28) |
Risk of Discontinuation | |||||
Fludrocortisone | 1103 | 298 | 268 (119, 816) | Reference | Reference |
Midodrine | 664 | 169 | 304 (133, 865) | 0.93 (0.77, 1.11) | 0.97 (0.80, 1.18) |