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Acute TMT exposure induced oxidative stress and inflammation at 24h. Heart mRNA expression of: (A) interleukin-6 (IL-6); (B) tumor necrosis factor-α (TNF-α); (C) ratio TNF-α to IL-6 mRNA; (D) interleukin-1β (IL-1β); (E) ratio IL-1β to IL-6; (F) caspase-3; and (G) thiobarbituric acid reactive substances (TBARS) content in the heart. Serum levels of (H) angiotensin-II and (I) IL-6. Data are expressed as mean ± s.e.m. (n = 10-12). * p<0.05; ** p<0.01.
