Table 1.
Immunohistochemical results for each tumor morphology.
| Morphology | AE1/3 | CK7 | Vim | NE | CA19-9 | AFP | Hep | CD117 | P53 | Ki67 |
|---|---|---|---|---|---|---|---|---|---|---|
| Adeno | ++ | ++ | − | + | + | Focal | Focal | − | + | 50% |
| Clear cell | + | + | − | Scattered single cells | + | Focal | + | − | + | 20% |
| LCNEC | + | ++ | − | + | − | − | Focal | + | + | 80% |
| Spindle | Focal | Focal | + | Focal | Focal | − | − | − | + | 50% |
Adeno: adenocarcinoma; LCNEC: large cell neuroendocrine carcinoma; spindle: spindle cell carcinoma; AE1/3: cytokeratin cocktail AE1/AE3; CK7: cytokeratin 7; Vim: vimentin; NE: neuroendocrine markers chromogranin, synaptophysin, and CD56; AFP: alpha fetoprotein; Hep: Hep Par 1; LCNEC: large cell neuroendocrine carcinoma.