Table 1.
Normalized minute ventilation, respiratory frequency and tidal volume values during the 5 min-exposure to hypercarbia expressed as a fraction of the baseline value (in air alone) and given as mean ± SE (n)
| Intervention | Normalized minute ventilation (Vmin) |
Normalized respiratory frequency (nfinst) |
Normalized tidal volume (nTV) |
||||||
|---|---|---|---|---|---|---|---|---|---|
| Saline | Gentamicin |
P value1 |
Saline | Gentamicin |
P value1 |
Saline | Gentamicin | P value1 | |
| Unilateral IT |
3.46 ± 0.50 (9) | 2.42 ± 0.18 (19) | 0.009* | 1.93 ± 0.20 (9) | 1.59 ± 0.10 (19) | 0.075 | 1.84 ± 0.18 (9) | 1.40 ± 0.07 (19) | 0.010* |
| Bilateral IT | 3.32 ± 0.44 (7) | 1.56 ± 0.06 (9) | 0.001* | 1.50 ± 0.26 (7) | 1.26 ± 0.06 (9) | 0.298 | 1.63 ± 0.24 (7) | 1.17 ± 0.07 (9) | 0.062 |
*
P < 0.05.
1
P value calculations included post hoc Bonferroni correction indicating whether bilateral and unilateral IT-Gent group differed from corresponding control groups.