Skip to main content
. Author manuscript; available in PMC: 2014 Nov 13.
Published in final edited form as: Chem Rev. 2013 Sep 16;113(11):8423–8455. doi: 10.1021/cr400158h

Table 2.

CTD-Associated Cyclin-Dependant Kinases

human S.cerevisiae S.pombe AKA CTD P-sit
CDK7 Cdk7/cyclin H/Mat1 Kin28/Ccl1/Tfb3 Mcs6/Msc2/Pmh1 TFFIIH kinase Ser5, S
CAK = CDK7 CAK = Cak1 CAK=Csk1
CDK9 Cdk9/cyclin T Bur1/Bur2 Cdk9/Pch1 P-TEFb Ser2, Ser5
CAK=CDK7 CAK = Cak1 CAK = Csk1
CDK12 Cdk12/cyclin K
Cdk13/cyclin K
Ctk1/Ctk2/Ctk3 Lsk1/Lsc1 CTDK-I Ser2, Ser5
CAK = CDK7 CAK = Cak1 CAK = Csk1
CDK8 Cdk8/cyclin C/MED12/MED13 Ssn3/Ssn8/Srb8/Ssn2 Cdk8/CycC/Med12/Med13 Mediator CDK module (CKM) Ser2, S
CAK = none? CAK = none? CAK = none?